C60

Description

The C60 fullerene, thanks to its small size, can easily cross the so-called blood-brain barrier. This property can lead to numerous medical applications, especially in the field of nanomedicines, through the implementation of new active compounds that could be used by the brain.

Fullerenes are relatively safe and inert, and yet have properties that allow the substance to create active derivatives.

Advantages

  • Solvent-free

  • Environmentally friendly synthesis using renewable energy
    (hydroelectric powered plant in Quebec)

Applications

  • Treatment of various neuronal problems.

  • Development of new drugs for the brain, associating its antioxidant and antiaggregant properties.

  • Biomedical applications, like the design of high-performance MRI contrast agents and X-ray imaging contrastagents. [1] [2]

  • Light-activated antimicrobial agents. [3]

  • Used as a carrier for gene and drug delivery systems.

  • They are used for serum protein profiling as MELDI material for biomarker discovery.

  • Potential antiviral activity, which has strong implications on the treatment of HIV-infection.

  • Anti-aging agent in the cosmetic sector.

  • Fullerenes can be made to be absorbed by HeLa cells. Recent experiments using HeLa cells in cancer research involves the development of new photosensitizers with increased ability to be absorbed by cancer cells and still trigger cell death. It is also important that a new photosensitizer does not stay in the body for a long time to prevent unwanted cell damage. [4]

References

Studied properties of fullerene derivatives:

title pharma
C60

Fullerene Carbon C60

SOL5060

99.99% Purity

Solvent Free

Buckminster Fullerene

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IC60BA

Description

Fullerenes have attracted the attention due to their potential as antiviral agents and several studies indicate that fullerene derivatives are possible candidates for the development of novel anti-influenza drugs.

Fullerenes have generated considerable interest for their unique structural and chemical properties.

Advantages

  • Antiproliferative and antibacterial activity

  • Excellent antioxidant activity

  • Inhibitor of HIV-reverse transcriptase

Applications

  • Why is it important to look for new drugs?.

  • Quick development of drug-resistance.

  • Frequent mutations of strains.
  • To have especially active small molecular inhibitors in controlling pandemics while vaccines are developed.

References

title pharma
IC60BA

IC60BA

SOL5065

>99.5% (A)

Indene C60 Bis Adduct

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Fullerenol C60

Description

Many of the proposed fullerene applications are to be practical technologies in a wide range of areas such as IT devices, diagnostics, pharmaceuticals, environmental, and energy industries. The direct application of fullerene and their derivatives to biological targets is now yielding promising applications in medicine.

Such attention to them is caused by unique chemical and physical properties of the fullerene core, including their photodynamic properties. The hydrophobic spheroid and the radical sponge character of fullerene are responsible for the activity in different fields.

Advantages

  • Solvent-free

  • Green chemistry

  • Environmentally friendly synthesis using renewable energy
    (hydroelectric powered plant in Quebec)

Applications

  • Antimicrobial activity.

  • Carrier for gene and drug delivery systems.

  • Pro-oxidants.

  • Cytotoxic or protective effect respectively against cancer cells or healthy cells.

  • Transfer of contrast agents or in drug transport.

  • Protect neurons in the particular areas of the brain.

  • Application in neuroscience.

  • Diagnostic application.

  • In the future provide a solid alternative to currently used pharmacological methods in chemotherapy, treatment of neurodegenerative diseases and radiobiology.

References

title pharma
sol5369

Fullerenol C60

SOL5369

99.99% Purity

solvent free

C60(OH)n n = 30-50

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