Neurovium C60

Neurovium and its applications in Biotechnology field

The NEUROVIUM C60 is a research-grade fullerene C60 engineered for applications in pharmaceutical and biotechnology research. With a unique hollow carbon-cage structure, fullerene C60 acts as a multi-radical scavenger, neutralizing reactive oxygen and nitrogen species and mimicking the activity of natural antioxidant enzymes such as superoxide dismutase (SOD).

Synthesized via a Solvent-Free Method. [1]

Green chemistry.

Environmentally friendly synthesis using renewable energy. [2]

[1] Solvents and volatiles are removed by subjecting the C60 to a controlled heat-cool process under dynamic inert medical nitrogen in order to suppress oxidation and preserve its pristine nature.
[2] Hydroelectric powered plant in Quebec.

Neurovium C60 Applications in Biotech

• Neuroprotection: Fullerenes and fullerenols have shown protective effects in neuronal models, reducing apoptosis and oxidative stress in neurodegenerative disease research.
• Oxidative Stress Modulation: Studies demonstrate fullerenes’ capacity to reduce oxidative damage and lipid peroxidation, relevant for cardiovascular, renal, and hepatic research.
• Drug Delivery Nanocarriers: The spherical structure and functionalizability of C60 enable conjugation with drugs, peptides, or nucleic acids for targeted delivery.
• Anti-viral and Anti-proliferative Research: Fullerene derivatives have been investigated for inhibitory effects on viral proteases and in oncology-related studies.

References

Studied properties:

1 Injac, R. et al. “Protective effects of fullerenol C60(OH)24 against doxorubicin-induced cardiotoxicity in rats”
(2009) Biomaterials.

2 Injac, R. et al. “Neuroprotective potential of fullerenol nanoparticles”
(2011) Pharmacol. Reports.

3 Gharbi, N. et al. “[60] Fullerene is a powerful antioxidant in vivo with no acute toxicity”
(2005) Toxicol. Lett.

4 Andrievsky, G.V. et al. “Study of aqueous fullerenol as a radical sponge”
(2002) J. Nanoscience Nanotech.

5 MST Nano. “Fullerenol nanoparticles: antioxidant and protective properties”
(2024) (neuro-, hepato-, nephroprotective).

Neurovium WS C60

Neurovium water soluble C60 and its applications in Biotechnology field

The NEUROVIUM WS C60 is a research-grade fullerenol C60(OH)x, the water-soluble derivative of fullerene C60, engineered for pharmaceutical and biotechnology research.

Hydroxylation makes C60 dispersible in aqueous media, enabling use in biological systems, neurodegenerative disease models, oxidative stress assays, and nanomedicine. With strong radical-scavenging capacity, fullerenol mimics superoxide dismutase (SOD) activity and has been studied for neuroprotection, organ protection, and drug delivery systems.

Synthesized via a Solvent-Free Method. [1]

Green chemistry.

Environmentally friendly synthesis using renewable energy. [2]

[1] Solvents and volatiles are removed by subjecting the C60 to a controlled heat-cool process under dynamic inert medical nitrogen in order to suppress oxidation and preserve its pristine nature.
[2] Hydroelectric powered plant in Quebec.

Neurovium WS C60 Applications in Biotech

• Neuroprotection: Fullerenol nanoparticles reduce oxidative stress, inhibit neuronal apoptosis, and show potential in models of neurodegenerative disease.

References

Studied properties:

1 Injac, R. et al. “Fullerenol C60(OH)24 protects against doxorubicin-induced cardiotoxicity”
(2009) Biomaterials.

2 Injac, R. et al. “Neuroprotective potential of fullerenol nanoparticles in oxidative stress models”
(2011) Pharmacol. Reports.

3 Gharbi, N. et al. “[60] Fullerene and fullerenols are powerful antioxidants in vivo with no acute toxicity”
(2005) Toxicol. Lett.

4 Andrievsky, G.V. et al. “C60 fullerenols as radical sponges in aqueous systems”
(2002) J. Nanoscience Nanotech.

5 MST Nano. “Fullerenol nanoparticles: antioxidant, neuroprotective, and organ-protective effects”
(2024).