NEUROVIUM

Description

NEUROVIUM – Pharma/Biotech

NEUROVIUM C60 is a research-grade fullerene C60 engineered for applications in pharmaceutical and biotechnology research. With a unique hollow carbon-cage structure, fullerene C60 acts as a multi-radical scavenger, neutralizing reactive oxygen and nitrogen species and mimicking the activity of natural antioxidant enzymes such as superoxide dismutase (SOD).

Key Applications in Pharma & Biotech Research:

• Neuroprotection: Fullerenes and fullerenols have shown protective effects in neuronal models, reducing apoptosis and oxidative stress in neurodegenerative disease research

• Oxidative Stress Modulation: Studies demonstrate fullerenes’ capacity to reduce oxidative damage and lipid peroxidation, relevant for cardiovascular, renal, and hepatic research

• Drug Delivery Nanocarriers: The spherical structure and functionalizability of C60 enable conjugation with drugs, peptides, or nucleic acids for targeted delivery .

• Anti-viral and Anti-proliferative Research: Fullerene derivatives have been investigated for inhibitory effects on viral proteases and in oncology-related studies

 

SOLVENT FREE GRADE:
Grade: 99.99%  (SOL5060-NV-YY) – Solvent-free* – ™ Very Ultra High Purity grade

 

SUBLIMED GRADE:
Grade: 99.99%  (SOL5060-NV-S) – Solvent-free* – ™ Very Ultra High Purity grade

 

™ *products:

These C60 products are going through further processes in order to be highly soluble in organic solvents, oils and other related medias.
Time to dissolve/disperse in (provided as a guideline only):
Toluene: Few seconds to few minutes (max 3 g/L)
o-DCB: Few seconds to few minutes (max 24 g/L)
Olive oil: 3-5 days (to 0.8-1g/L, vs 2 weeks for most common C60 powder)

*Solvents and volatiles are removed by subjecting the C60 to a controlled heat-cool process under dynamic inert medical nitrogen in order to suppress oxidation and preserve its pristine nature.

 

Safety Data Sheet: SDS-Neurovium-C60
Certificate of Analyses: COA-Neurovium-C60

PROMOTIONAL MATERIALS – Flyer (English)

Technical Data Sheet: TDS-Neurovium-C60

Acronyms:	C60
Chemical Name:	Fullerene C60
CAS#	99685-96-8
Color and Texture:	brown to dark grey
Molecular Weight:	720.64 g/mol
Absorption, λmax (Media):	N/A

 

Emission, λmax (Media):	N/A
HOMO (eV):	-6.1 eV
LUMO (eV):	-4.3 eV
Melting point (°C):	> 280 °C (> 536 °F) (lit.)
Solubility (Solvent):	Toluene, oils, o-DCB
Other:	N/A

 

References:

1. Injac, R. et al. Protective effects of fullerenol C60(OH)24 against doxorubicin-induced cardiotoxicity in rats. Biomaterials (2009).

2. Injac, R. et al. Neuroprotective potential of fullerenol nanoparticles. Pharmacol. Reports (2011).

3. Gharbi, N. et al. [60]Fullerene is a powerful antioxidant in vivo with no acute toxicity. Toxicol. Lett. (2005).

4. Andrievsky, G.V. et al. Study of aqueous fullerenol as a radical sponge. J. Nanoscience Nanotech. (2002).

5. MST Nano. Fullerenol nanoparticles: antioxidant and protective properties (neuro-, hepato-, nephroprotective). (2024)

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* Price subject to change without prior notice

Products for Research and Development. Laboratory use only by qualified personnel. The user should read the available SDS and be aware of any precautions to take for the safe manipulation of these materials. Solarischem shall not be held responsible for any damage resulting from the use or handling of these products. Any product can be discontinued, specifications altered or price changed at any time without prior notice. The specifications and structures do not guarantee any product’s suitability for the client’s applications or uses.