High-Purity WSC60MA C60 Malonic Acid | Leading Manufacturer

WSC60MA – C60 Malonic Acid

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SOL5163

WSC60MA, Water-Soluble Fullerene derivatives can be used in medicinal research for the domain of neurodegenerative diseases, cancer, viral infection, and drug tolerances for its properties as antioxidant, antibacterial, and antiproliferative agent. This product can be custom-made with various counter ions. Solaris offers different level of malonic acid substitutions with n >3, n>4, and n>5 malonic acid attached to the C60 core. The C60 core used to make these materials is >99.99% pure.

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Description

WSC60MA – C60 Malonic Acid (SOL5163): High-Purity Water-Soluble Fullerene Precursor

Overview of WSC60MA

WSC60MA C60 Malonic Acid (SOL5163) is a highly specialized methanofullerene C60 derivative functionalized with malonic acid groups. It is specifically engineered for applications requiring high solubility in basic aqueous media. As a leading C60 malonic acid manufacturer, Solaris Chem produces this material under rigorous quality control standards to ensure that every batch retains the precise electronic and biological properties required for advanced nanotechnology and medicinal chemistry.

Unlike pristine fullerenes, which are inherently hydrophobic and difficult to process in biological environments, WSC60MA acts as a versatile bridge. It allows the unique carbon cage of C60 to interact with aqueous systems without sacrificing its powerful electron-accepting capabilities.

Functionalization Levels and Customization (n > 3, 4, 5)

One of the primary competitive advantages of Solaris Chem is our ability to offer various degrees of substitution for the SOL5163 precursor. Understanding these levels is critical for the success of your research or formulation:

  • Level n > 3 (SOL5163A): Provides an optimal balance between maintaining the core C60 properties and achieving reliable solubility.

  • Level n > 4 (SOL5163B): Increases the surface charge density, making it ideal for applications involving strong electrostatic interactions.

  • Level n > 5 (SOL5163C): Our highest functionalization grade, optimized for maximum solubility in basic water and enhanced stability in complex chemical formulations.

This ability to customize the product with various counter ions allows  WSC60MA C60 Malonic Acid (SOL5163) to be fine-tuned for specific experimental protocols, ranging from in vitro assays to advanced drug delivery models.

Cutting-Edge Applications in Medicinal Research

The potential of WSC60MA lies in its unique molecular geometry, which allows it to function as a potent antioxidant and therapeutic scaffold.

1. Neuroprotection and Oxidative Stress

The C60 core is famously known as a “radical sponge.” WSC60MA is frequently utilized in studies regarding neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, to neutralize reactive oxygen species (ROS) that contribute to neuronal damage. Its water-soluble nature makes it significantly easier to study in aqueous cellular environments.

2. Antiviral Properties (COVID-19 and Influenza)

Recent scientific literature (Ref. 1 & 2) has highlighted the ability of C60 derivatives to interfere with viral transmission mechanisms. WSC60MA has been a subject of intense study for its capacity to alter viral surfaces and combat the transmission of pathogens like COVID-19 and the Influenza virus, positioning it as a key component in the development of next-generation antiviral agents.

3. Oncology and Antiproliferative Agents

The capacity of SOL5163 to interact with cell membranes and specific enzymes makes it a prime candidate for oncological research. It is studied as an antiproliferative agent, capable of inhibiting cancer cell growth through selective cellular signaling mechanisms.

 

Safety Data Sheet – SDS-SOL5163

Technical Data Sheet:

Acronyms: WSC60MA
Chemical Name: C60- n-(malonic acid), Water Soluble C60
CAS# N/A
Color and Texture: brown to black powder
Molecular Weight: N/A
Absorption, λmax (Media): N/A
Emission, λmax (Media): N/A
HOMO (eV): N/A
LUMO (eV): N/A
Melting point (°C): N/A
Solubility (Solvent): Water, basic (pH > 7)
Other: N/A

Ref.

(1) “Surface Alterations to Impart Antiviral Properties to Combat COVID‑19 Transmission”, Author(s): Reshma Y. Siddiquie, Amit Agrawal, Suhas S. Joshi. © Indian National Academy of Engineering 2020. https://doi.org/10.1007/s41403-020-00096-9

(2) “Anti-Influenza Activity of C60 Fullerene Derivatives”, Author(s): Masaki Shoji, Etsuhisa Takahashi, Dai Hatakeyama, Yuma Iwai, Yuka Morita, Riku Shirayama, Noriko Echigo, Hiroshi Kido, Shigeo Nakamura, Tadahiko Mashino, Takeshi Okutani, Takashi Kuzuhara. June 13. https://doi.org/10.1371/journal.pone.0066337

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Products for Research and Development. Laboratory use only by qualified personnel. The user should read the available SDS and be aware of any precautions to take for the safe manipulation of these materials. Solarischem shall not be held responsible for any damage resulting from the use or handling of these products. Any product can be discontinued, specifications altered or price changed at any time without prior notice. The specifications and structures do not guarantee any product’s suitability for the client’s applications or uses.

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